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Professor Nicki Panoskaltsis
Professor in Personalised Therapeutics, Pharmacy

Publications and Further Research Outputs

Peer-Reviewed Publications

Murnane C., Gardiner N., Crehan O., Bacon C.L., McHugh R., Gilmer J.F., Mantalaris A., Panoskaltsis N., Chimeric Antigen Receptor-T (CAR-T) Cells as " Living Drugs ": A Clinical Pharmacist Perspective, Journal of Clinical Pharmacy and Therapeutics, 2024, 2024 Journal Article, 2024 DOI

de Janon A, Mantalaris A, Panoskaltsis N., Three-Dimensional Human Bone Marrow Organoids for the Study and Application of Normal and Abnormal Hematoimmunopoiesis., Journal of immunology (Baltimore, Md. : 1950), 210, (7), 2023, p895-904 Journal Article, 2023 DOI

Perl A.E., Hosono N., Montesinos P., Podoltsev N., Martinelli G., Panoskaltsis N., Recher C., Smith C.C., Levis M.J., Strickland S., Rollig C., Gross-Langenhoff M., Chou W.-C., Lee J.-H., Yokoyama H., Hasabou N., Lu Q., Tiu R.V., Altman J.K., Clinical outcomes in patients with relapsed/refractory FLT3-mutated acute myeloid leukemia treated with gilteritinib who received prior midostaurin or sorafenib, Blood Cancer Journal, 12, (5), 2022 Journal Article, 2022 DOI

Allenby M.C., Okutsu N., Brailey K., Guasch J., Zhang Q., Panoskaltsis N., Mantalaris A., A Spatiotemporal Microenvironment Model to Improve Design of a Three-Dimensional Bioreactor for Red Cell Production, Tissue Engineering - Part A, 28, (1-2), 2022, p38 - 53, p38-53 Journal Article, 2022 DOI

McCarthy N.E., Stagg A.J., Price C.L., Mann E.R., Gellatly N.L., Al-Hassi H.O., Knight S.C., Panoskaltsis N., Patients with gastrointestinal irritability after TGN1412-induced cytokine storm displayed selective expansion of gut-homing "ß and ""T cells, Cancer Immunology, Immunotherapy, 70, (4), 2021, p1143 - 1153, p1143-1153 Journal Article, 2021 DOI

Panoskaltsis N., Are all cytokine storms the same?, Cancer Immunology, Immunotherapy, 70, (4), 2021, p887 - 892, p887-892 Journal Article, 2021 DOI

Panoskaltsis N., McCarthy N.E., Knight S.C., Myelopoiesis of acute inflammation: lessons from TGN1412-induced cytokine storm, Cancer Immunology, Immunotherapy, 70, (4), 2021, p1155 - 1160, p1155-1160 Journal Article, 2021 DOI

Panoskaltsis N., McCarthy N.E., Stagg A.J., Mummery C.J., Husni M., Arebi N., Greenstein D., Price C.L., Al-Hassi H.O., Koutinas M., Mantalaris A., Knight S.C., Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm, Cancer Immunology, Immunotherapy, 70, (4), 2021, p1127 - 1142, p1127-1142 Journal Article, 2021 DOI

Dennis M., Burnett A., Hills R., Thomas I., Ariti C., Severinsen M.T., Hemmaway C., Greaves P., Clark R.E., Copland M., Russell N., Kallenbach M., Culligan D., Duncan C., Krishnamurthy P., Cuthbert A., Patalappa C., Spanoudakis M., Galvani D., Berkahn I., Patton N., Pemberton L., Virchis A., Jasani P., Parker A., Arnold C., Cuthbert R., Finnega D., Nikolousis M., Pratt G., Cahalin P., Ackroyd S., Mehta P., Protheroe R., Weinkove R., Ali S., Welch E., Smith M., Spearing R., Vyas P., Campbell G., Hamblin M., Wood M., Gupta S., Westonsmith S., Pillai A., Hunter H., Rule S., Neilson R., Lush R., Rothwell K., Swe W., Chalmers I., Prahladan M., Kwan M., Lyttleton M., Hunter A., Martin A.M., Saravanamuttu K., Saif M., Tholouli E., Andrews V., Jackson S., Rajagopal R., Morrison A., Gordon W., Mitchell L., Bowen A., McGrann A., Mittal S., Panoskaltsis N., Byrne J., Das-Gupta E., Radia R., Baker B., Kilfoyle A., Knottenbelt E., Rinaldi C., Moreton P., Furby D., Jack F., Alderman C., Belsham E., Corser R., Cranfield T., Dignum H., James C., Gudgin E., Mohan M., Kampman P., Kjeldsen L., Mourek J., Nielsen O.J., Niemann C.U., Grech H., Khan A., Sampson R., Creagh D., Szabo F., Coppell J., Veale D., Kottaridis P., Fernandes S., Cullis J., Grand E., Wandroo F., Mohite U., O'Brien D., Nicholson T., Janes S., Aitchison R., Galloway M., Mathew S., Blesing N., Green S., Mamadigi R., Plews D., Chacko J., Salim R., Allameddine A., Greenfield H., Osborne D., Hodges G., Lai H.C., Carrington P., Sadik W., Yung L., Lokare A., Alvares C., Knapper S., Goodman H., Islam S., Aitchison R., Pattinson J., Pushkaran B., Heartin E., Edwards D., Seale J., A randomised evaluation of low-dose cytosine arabinoside (ara-C) plus tosedostat versus low-dose ara-C in older patients with acute myeloid leukaemia: results of the LI-1 trial, British Journal of Haematology, 194, (2), 2021, p298 - 308, p298-308 Journal Article, 2021 DOI

Karakostas P., Panoskaltsis N., Mantalaris A., Georgiadis M.C., Optimization of CAR T-cell therapies supply chains, Computers and Chemical Engineering, 139, 2020 Journal Article, 2020 DOI

Abdelaal Ahmed Mahmoud M Alkhatip, A., Conroy, P., Hamza, M.K., Murphy, I., Purcell, A., McGuire, D., The authors reply, Critical Care Medicine, 48, (8), 2020, pE731-E732 Journal Article, 2020

Allenby M.C., Panoskaltsis N., Tahlawi A., Dos Santos S.B., Mantalaris A., Dynamic human erythropoiesis in a three-dimensional perfusion bone marrow biomimicry, Biomaterials, 188, 2019, p24 - 37, p24-37 Journal Article, 2019 TARA - Full Text DOI

Gyorgy R., Klontzas M.E., Kostoglou M., Panoskaltsis N., Mantalaris A., Georgiadis M.C., Capturing mesenchymal stem cell heterogeneity during osteogenic differentiation: an experimental-modeling approach, Industrial and Engineering Chemistry Research, 58, (31), 2019, p13900 - 13909, p13900-13909 Journal Article, 2019 DOI

Klontzas M.E., Reakasame S., Silva R., Morais J.C.F., Vernardis S., MacFarlane R.J., Heliotis M., Tsiridis E., Panoskaltsis N., Boccaccini A.R., Mantalaris A., Oxidized alginate hydrogels with the GHK peptide enhance cord blood mesenchymal stem cell osteogenesis: A paradigm for metabolomics-based evaluation of biomaterial design, Acta Biomaterialia, 88, 2019, p224 - 240, p224-240 Journal Article, 2019 DOI

Mortera-Blanco T., Rende M., Panoskaltsis N., Mantalaris A., Tissue engineering of normal and abnormal bone marrow, Comprehensive Biotechnology, 2019, p225 - 235, p225-235 Journal Article, 2019 DOI

Tahlawi A., Klontzas M.E., Allenby M.C., Morais J.C.F., Panoskaltsis N., Mantalaris A., RGD-functionalized polyurethane scaffolds promote umbilical cord blood mesenchymal stem cell expansion and osteogenic differentiation, Journal of Tissue Engineering and Regenerative Medicine, 13, (2), 2019, p232 - 243, p232-243 Journal Article, 2019 DOI

Allenby M.C., Tahlawi A., Morais J.C.F., Li K., Panoskaltsis N., Mantalaris A., Ceramic hollow fibre constructs for continuous perfusion and cell harvest from 3D hematopoietic organoids, Stem Cells International, 2018, 2018 Journal Article, 2018 DOI

Misener R., Allenby M.C., Fuentes-Gari M., Gupta K., Wiggins T., Panoskaltsis N., Pistikopoulos E.N., Mantalaris A., Stem cell biomanufacturing under uncertainty: A case study in optimizing red blood cell production, AIChE Journal, 64, (8), 2018, p3011 - 3022, p3011-3022 Journal Article, 2018 DOI

Quiroga-Campano A.L., Panoskaltsis N., Mantalaris A., Energy-based culture medium design for biomanufacturing optimization: A case study in monoclonal antibody production by GS-NS0 cells, Metabolic Engineering, 47, 2018, p21 - 30, p21-30 Journal Article, 2018 DOI

Vernardis S.I., Terzoudis K., Panoskaltsis N., Mantalaris A., Human embryonic and induced pluripotent stem cells maintain phenotype but alter their metabolism after exposure to ROCK inhibitor, Scientific Reports, 7, 2017 Journal Article, 2017 DOI

Harrison C.N., Mead A.J., Panchal A., Fox S., Yap C., Gbandi E., Houlton A., Alimam S., Ewing J., Wood M., Chen F., Coppell J., Panoskaltsis N., Knapper S., Ali S., Hamblin A., Scherber R., Dueck A.C., Cross N.C.P., Mesa R., McMullin M.F., Ruxolitinib vs best available therapy for et intolerant or resistant to hydroxycarbamide, Blood, 130, (17), 2017, p1889 - 1897, p1889-1897 Journal Article, 2017 DOI

Gyorgy R., Klontzas M.E., Kostoglou M., Panoskaltsis N., Georgiadis M.C., Mantalaris A., An Integrated Experimental-Modelling Approach of Mesenchymal Stem Cell Bioprocess towards Osteogenic Differentiation, IFAC-PapersOnLine, 50, (1), 2017, p9877 - 9882, p9877-9882 Journal Article, 2017 DOI

Allenby M.C., Misener R., Panoskaltsis N., Mantalaris A., A Quantitative Three-Dimensional Image Analysis Tool for Maximal Acquisition of Spatial Heterogeneity Data, Tissue Engineering - Part C: Methods, 23, (2), 2017, p108 - 117, p108-117 Journal Article, 2017 DOI

Gyorgy R., Klontzas M.E., Kostoglou M., Panoskaltsis N., Mantalaris A., Georgiadis M.C., A Population Balance Model for Stem Cell Differentiation Bioprocesses, Computer Aided Chemical Engineering, 40, 2017, p2761 - 2766, p2761-2766 Journal Article, 2017 DOI

Savvopoulos, S., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., A Personalized Framework for Dynamic Modeling of Disease Trajectories in Chronic Lymphocytic Leukemia, IEEE Transactions on Biomedical Engineering, 63, (11), 2016, p2396-2404 Journal Article, 2016 DOI

Chaudhry, M.S., Gilmour, K.C., House, I.G., Layton, M., Panoskaltsis, N., Sohal, M., Trapani, J.A., Voskoboinik, I., Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition, OncoImmunology, 5, (7), 2016 Journal Article, 2016 DOI

Kostoglou, M., Fuentes-Garí, M., García-Münzer, D., Georgiadis, M.C., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., A comprehensive mathematical analysis of a novel multistage population balance model for cell proliferation, Computers and Chemical Engineering, 91, 2016, p157-166 Journal Article, 2016 DOI

Fauzi, I., Panoskaltsis, N., Mantalaris, A., In vitro differentiation of embryonic stem cells into hematopoietic lineage: Towards erythroid progenitor"s production, Methods in Molecular Biology, 1341, 2015, p217-234 Journal Article, 2015 DOI

Velliou, E.G., Dos Santos, S.B., Papathanasiou, M.M., Fuentes-Gari, M., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Towards unravelling the kinetics of an acute myeloid leukaemia model system under oxidative and starvation stress: A comparison between two- and three-dimensional cultures, Bioprocess and Biosystems Engineering, 38, (8), 2015, p1589-1600 Journal Article, 2015 DOI

Burnett, A.K., Russell, N., Hills, R.K., Panoskaltsis, N., Khwaja, A., Hemmaway, C., Cahalin, P., Clark, R.E., Milligan, D., A randomised comparison of the novel nucleoside analogue sapacitabine with low-dose cytarabine in older patients with acute myeloid leukaemia, Leukemia, 29, (6), 2015, p1312-1319 Journal Article, 2015 DOI

Dennis, M., Russell, N., Hills, R.K., Hemmaway, C., Panoskaltsis, N., McMullin, M.-F., Kjeldsen, L., Dignum, H., Thomas, I.F., Clark, R.E., Milligan, D., Burnett, A.K., Vosaroxin and vosaroxin plus low-dose Ara-C (LDAC) vs low-dose Ara-C alone in older patients with acute myeloid leukemia, Blood, 125, (19), 2015, p2923-2932 Journal Article, 2015 DOI

Fuentes-Garí, M., Misener, R., Georgiadis, M.C., Kostoglou, M., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., Selecting a Differential Equation Cell Cycle Model for Simulating Leukemia Treatment, Industrial and Engineering Chemistry Research, 54, (36), 2015, p8847-8859 Journal Article, 2015 DOI

Fuentes-Garí, M., Misener, R., Pefani, E., García-Münzer, D., Kostoglou, M., Georgiadis, M.C., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Cell cycle model selection for leukemia and its impact in chemotherapy outcomes, Computer Aided Chemical Engineering, 37, 2015, p2159-2164 Journal Article, 2015 DOI

Fuentes-Garí, M., Velliou, E., Misener, R., Pefani, E., Rende, M., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., A systematic framework for the design, simulation and optimization of personalized healthcare: Making and healing blood, Computers and Chemical Engineering, 81, 2015, p80-93 Journal Article, 2015 DOI

Fuentes-Garí, M., Misener, R., García-Munzer, D., Velliou, E., Georgiadis, M.C., Kostoglou, M., Pistikopoulos, E.N., Panoskaltsis, N., Mantalaris, A., A mathematical model of subpopulation kinetics for the deconvolution of leukaemia heterogeneity, Journal of the Royal Society Interface, 12, (108), 2015 Journal Article, 2015 DOI

Fuentes-Ga", M., Misener, R., Georgiadis, M.C., Kostoglou, M., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Chemotherapy optimization in Leukemia: Selecting the right mathematical models for the right biological processes, IFAC-PapersOnLine, 28, (20), 2015, p534-539 Journal Article, 2015 DOI

Savvopoulos, S., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Global Sensitivity Analysis for a Model of B-Cell Chronic Lymphocytic Leukemia Disease Trajectories, Computer Aided Chemical Engineering, 37, 2015, p185-190 Journal Article, 2015 DOI

Kostoglou, M., Fuentes-Garí, M., García-Münzer, D., Georgiadis, M.C., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Mathematical analysis of multistage population balances for cell growth and death, Computer Aided Chemical Engineering, 37, 2015, p2105-2110 Journal Article, 2015 DOI

Fauzi, I., Panoskaltsis, N., Mantalaris, A., Early exposure of murine embryonic stem cells to hematopoietic cytokines differentially directs definitive erythropoiesis and cardiomyogenesis in alginate hydrogel three-dimensional cultures, Stem Cells and Development, 23, (22), 2014, p2720-2729 Journal Article, 2014 DOI

Fuentes-Gari, M., Misener, R., Garcia-Munzer, D., Velliou, E., Georgiadis, M.C., Kostoglou, M., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Towards personalized treatments for leukemia based on cell cycle heterogeneity: An experimental/modeling approach, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting, 1, 2014, p210-211 Journal Article, 2014

Misener, R., Fuentes-Garí, M., Velliou, E.G., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Robust design and operation of red blood cell production in a parallelised hollow fibre bioreactor, Computing and Systems Technology Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting, 2, 2014, p803-805 Journal Article, 2014

Savvopoulos, S., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., A personalized framework for dynamic modelling of chronic lymphocytic leukemia disease trajectories, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting, 2, 2014, p999-1001 Journal Article, 2014

Velliou, E., Fuentes-Garí, M., Misener, R., Pefani, E., Rende, M., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., A framework for the design, modeling and optimization of biomedical systems, Computer Aided Chemical Engineering, 34, 2014, p225-236 Journal Article, 2014 DOI

Pefani E., Panoskaltsis N., Mantalaris A., Georgiadis M.C., Pistikopoulos E.N., Chemotherapy drug scheduling for the induction treatment of patients with acute myeloid leukemia, IEEE Transactions on Biomedical Engineering, 61, (7), 2014, p2049 - 2056, p2049-2056 Journal Article, 2014 TARA - Full Text DOI

Krieger, A., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Modeling and analysis of individualized pharmacokinetics and pharmacodynamics for volatile anesthesia, IEEE Transactions on Biomedical Engineering, 61, (1), 2014, p25-34 Journal Article, 2014 DOI

Misener, R., Fuentes Garí, M., Rende, M., Velliou, E., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Global superstructure optimisation of red blood cell production in a parallelised hollow fibre bioreactor, Computers and Chemical Engineering, 71, 2014, p532-553 Journal Article, 2014 DOI

Misener, R., Chin, J., Lai, M., Fuentes Garí, M., Velliou, E., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Robust superstructure optimisation of a bioreactor that produces red blood cells, Computer Aided Chemical Engineering, 33, 2014, p91-96 Journal Article, 2014 DOI

Fuentes Garí, M., Velliou, E.G., Misener, R., Brito Dos Santos, S., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., Towards a personalised treatment of acute myeloid leukaemia: The impact of considering the cell cycle, Materials Engineering and Sciences Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013, p678-680 Journal Article, 2013

Pefani, E., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Design of optimal patient-specific chemotherapy protocols for the treatment of acute myeloid leukemia (AML), Computers and Chemical Engineering, 57, 2013, p187-195 Journal Article, 2013 DOI

Garí, M.F., Velliou, E.G., Misener, R., Dos Santos, S.B., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., Towards a personalised treatment of acute myeloid leukaemia: The impact of considering the cell cycle, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013, p769-771 Journal Article, 2013

Velliou, E.G., Garí, M.F., Dos Santos, S.B., Misener, R., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., The effect of oxygen and glucose stress on the evolution of a leukaemia model system in an in vitro bone marrow biomimicry, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013, p573-575 Journal Article, 2013

Pefani, E., Panoskaltsis, N., Velliou, E., Fuentes, M., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., An automated system for the design of optimal personalized chemotherapy protocols for the treatment of Leukemia, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013, p362-364 Journal Article, 2013

Pefani, E., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Design of optimal disease and patient-specific chemotherapy protocols for the treatment of Acute Myeloid Leukaemia (AML), Computer Aided Chemical Engineering, 31, 2012, p1717-1721 Journal Article, 2012 DOI

Mortera-Blanco, T., Rende, M., Macedo, H., Farah, S., Bismarck, A., Mantalaris, A., Panoskaltsis, N., Ex vivo mimicry of normal and abnormal human hematopoiesis, Journal of Visualized Experiments, (62), 2012 Journal Article, 2012 DOI

Ma, C.Y.J., Panoskaltsis, N., Kumar, R., Xu, X.Y., Mantalaris, A., Simulation of ex vivo bone marrow culture: Application to chronic myeloid leukaemia growth model, Biochemical Engineering Journal, 61, 2012, p66-77 Journal Article, 2012 DOI

Lim, M., Shunjie, C., Panoskaltsis, N., Mantalaris, A., Systematic experimental design for bioprocess characterization: Elucidating transient effects of multi-cytokine contributions on erythroid differentiation, Biotechnology and Bioprocess Engineering, 17, (1), 2012, p218-226 Journal Article, 2012 DOI

Krieger, A., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Analysis of an individualized physiologically based model for anesthesia control, IFAC Proceedings Volumes (IFAC-PapersOnline), 45, (18), 2012, p385-390 Journal Article, 2012 DOI

Fauzi, I., Panoskaltsis, N., Mantalaris, A., Enhanced hematopoietic differentiation toward erythrocytes from murine embryonic stem cells with hepG2-conditioned medium, Stem Cells and Development, 21, (17), 2012, p3152-3161 Journal Article, 2012 DOI

Lim, M., Panoskaltsis, N., Ye, H., Mantalaris, A., Optimization of in vitro erythropoiesis from CD34+ cord blood cells using design of experiments (DOE), Biochemical Engineering Journal, 55, (3), 2011, p154-161 Journal Article, 2011 DOI

Krieger, A., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., A Novel Physiologically Based Compartmental Model for Volatile Anaesthesia, Computer Aided Chemical Engineering, 29, 2011, p1495-1499 Journal Article, 2011 DOI

Pefani, E., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E., Towards a high-fidelity model for model based optimisation of drug delivery systems in acute myeloid leukemia, Computer Aided Chemical Engineering, 29, 2011, p1505-1509 Journal Article, 2011 DOI

Mortera-Blanco T., Mantalaris A., Bismarck A., Aqel N., Panoskaltsis N., Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds, Biomaterials, 32, (35), 2011, p9263 - 9270, p9263-9270 Journal Article, 2011 DOI TARA - Full Text

Zubairi, S., Bismarck, A., Koutinas, A., Panoskaltsis, N., Mantalaris, A., Surface treatment of poly(3-hydroxybutyric acid) (PHB) and poly(3-hydroxybutyric-co-3-hydroxyvaleric acid) (PHBV) porous 3-D scaffolds with an improved thickness to enhance cell-biomaterial adhesion and interactions, 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials, 2011 Journal Article, 2011

Pefani, E., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Modelling and simulation of drug delivery systems for the treatment of acute myeloid leukemia, IFMBE Proceedings, 37, 2011, p259-262 Journal Article, 2011 DOI

Blanco T.M., Mantalaris A., Bismarck A., Panoskaltsis N., The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia, Biomaterials, 31, (8), 2010, p2243 - 2251, p2243-2251 Journal Article, 2010 DOI TARA - Full Text

Placzek, M.R., Chung, I.-M., Macedo, H.M., Ismail, S., Blanco, T.M., Lim, M., Jae, M.C., Fauzi, I., Kang, Y., Yeo, D.C.L., Ma, C.Y.J., Polak, J.M., Panoskaltsis, N., Mantalaris, A., Stem cell bioprocessing: Fundamentals and principles, Journal of the Royal Society Interface, 6, (32), 2009, p209-232 Journal Article, 2009 DOI

Lim, M., Ye, H., Panoskaltsis, N., Mantalaris, A., Optimal expansion and differentiation of cord blood stem cells using design of experiments, Handbook of Cardiac Stem Cell Therapy, 2008, p265-281 Journal Article, 2008

Yue, X., Drakakis, E.M., Lim, M., Radomska, A., Ye, H., Mantalaris, A., Panoskaltsis, N., Cass, A., A real-time multi-channel monitoring system for stem cell culture process, IEEE Transactions on Biomedical Circuits and Systems, 2, (2), 2008, p66-77 Journal Article, 2008 DOI

Kumar, R., Panoskaltsis, N., Stepanek, F., Mantalaris, A., Coupled oxygen-carbon dioxide transport model for the human bone marrow, Food and Bioproducts Processing, 86, (3), 2008, p211-219 Journal Article, 2008 DOI

Lim, M., Ye, H., Drakakis, E.M., Yue, X., Cass, A.E.G., Panoskaltsis, N., Mantalaris, A., Towards information-rich bioprocessing: Generation of spatio-temporal profiles through the use of design of experiments to determine optimal number and location of sensors-An example in thermal profiles, Biochemical Engineering Journal, 40, (1), 2008, p1-7 Journal Article, 2008 DOI

Xicai, Y., Drakakis, E.M., Hua, Y., Lim, M., Mantalaris, A., Panoskaltsis, N., Radomska, A., Toumazou, C., Cass, T., An on-line, multi-parametric, multi-channel physicochemical monitoring platform for stem cell culture bioprocessing, Proceedings - IEEE International Symposium on Circuits and Systems, 2007, p1215-1218 Journal Article, 2007

Lim, M., Ye, H., Panoskaltsis, N., Drakakis, E.M., Yue, X., Cass, A.E.G., Radomska, A., Mantalaris, A., Intelligent bioprocessing for haemotopoietic cell cultures using monitoring and design of experiments, Biotechnology Advances, 25, (4), 2007, p353-368 Journal Article, 2007 DOI

Pavlu, J., Jackson, M., Panoskaltsis, N., GM1-gangliosidosis type I, British Journal of Haematology, 135, (4), 2006, p422 Journal Article, 2006 DOI

Suntharalingam, G., Perry, M.R., Ward, S., Brett, S.J., Castello-Cortes, A., Brunner, M.D., Panoskaltsis, N., Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412, New England Journal of Medicine, 355, (10), 2006, p1018-1028 Journal Article, 2006 DOI

Kumar, R., Ngai, S., Bardsley, M., Panoskaltsis, N., Stepanek, F., Mantalaris, A., Bone marrow oxygen transport model in sickle cell disease, Proceedings of the 3rd IASTED International Conference on Biomedical Engineering 2005, 2005, p300-304 Journal Article, 2005

Panoskaltsis, N., Mantalaris, A., Wu, J.H.D., Engineering a mimicry of bone marrow tissue ex vivo, Journal of Bioscience and Bioengineering, 100, (1), 2005, p28-35 Journal Article, 2005 DOI

Pavlu, J., Panoskaltsis, N., Dysplastic polychromatic "snowmoblast", Blood, 106, (12), 2005, p3689 Journal Article, 2005 DOI

Panoskaltsis, N., Dendritic cells in MDS and AML - Cause, effect or solution to the immune pathogenesis of disease?, Leukemia, 19, (3), 2005, p354-357 Journal Article, 2005 DOI

Safinia, L., Panoskaltsis, N., Mantalaris, A., Haematopoietic culture systems, Bioreactors for Tissue Engineering: Principles, Design and Operation, 2005, p309-334 Journal Article, 2005

Panoskaltsis, N., Reid, C.D.L., Knight, S.C., Immune modulation with dendritic cells, Transfusion Medicine, 14, (2), 2004, p81-96 Journal Article, 2004 DOI

Panoskaltsis, N., Reid, C.D.L., Knight, S.C., Quantification and cytokine production of circulating lymphoid and myeloid cells in acute myelogenous leukaemia, Leukemia, 17, (4), 2003, p716-730 Journal Article, 2003 DOI

Panoskaltsis, N., Belanger, T.J., Liesveld, J.L., Abboud, C.N., Optimal cytokine stimulation for the enhanced generation of leukemic dendritic cells in short-term culture, Leukemia Research, 26, (2), 2002, p191-201 Journal Article, 2002 DOI

Mantalaris, A., Panoskaltsis, N., Sakai, Y., Bourne, P., Chang, C., Messing, E.M., David Wu, J.H., Localization of androgen receptor expression in human bone marrow, Journal of Pathology, 193, (3), 2001, p361-366 Journal Article, 2001 DOI

Liesveld, J.L., Rosell, K., Panoskaltsis, N., Belanger, T., Harbol, A., Abboud, C.N., Response of human CD34+ cells to CXC, CC, and CX3C chemokines: Implications for cell migration and activation, Journal of Hematotherapy and Stem Cell Research, 10, (5), 2001, p643-655 Journal Article, 2001 DOI

Panoskaltsis, N., Derman, M.P., Perillo, I., Brennan, J.K., Erratum: Thrombotic thrombocytopenic purpura in pulmonary-renal syndromes (American Journal of Hematology (2000) 65 (50-55)), American Journal of Hematology, 65, (3), 2000, p267 Journal Article, 2000 DOI

Panoskaltsis, N., Derman, M.P., Perillo, I., Brennan, J.K., Thrombotic thrombocytopenic purpura in pulmonary-renal syndromes, American Journal of Hematology, 65, (1), 2000, p50-55 Journal Article, 2000 DOI

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