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Our Research > Drug Development
Drug Development
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Design, chemical synthesis and evaluation of novel molecular structures as potential clinical drugs: for breast cancerand Burkitt’s Lymphoma
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Azetidinone analogues of Combretastatin A-4 as tubulin targeting agents
- Selective Estrogen receptor modulators and tubulin-targeting drugs
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Pro-drug optimisation of our current candidates
Synthesis and biochemistry of ER and tubulin antagonists
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Dual ER/aromatase and tubulin/aromatase targeting products
- Dual acting HSP 90 / tubulin targeting products
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Design of Multidrug resistance/P-glycoprotein modulators
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Natural Product Drug Discovery
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Anti-cancer lead discovery from Ethno-medicine (Sub-Saharan Africa, India and Pakistan) and evidence-based traditional Chinese medicine
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Anti-cancer lead discovery from natural sources (Marine, Terrestrial plants, fungi and microorganisms)
Cross-hybridisation of naturally occurring molecules to form novel anti-cancer scaffolds
Pharmacy Professors Associated with Disease, Drug Mechanisms & Safety