Trinity College Dublin

Skip to main content.

Top Level TCD Links

Workshop on Drug Transporters in the Lungs 2016 Programme

Please see below the links to the presentations from the Workshop and photographs taken on the day.

Thursday, 22nd September

Time Activity
08.30 - 08.45 Registration
08.45 - 09.00 Carsten Ehrhardt (TCD) - Opening Remarks
Session 1 Model systems for drug transporter studies in the lungs
Chair - Ryoko Tumoto
Rapporteurs - William Couet and Takeo Nakanishi
09.00 - 09.30 Tetsuya Terasaki (Tohoku University) - Human drug transporter protein expression in lung: Impact of quantitative targeted absolute proteomics (QTAP) for drug development in pulmonary disease
09.30 - 10.00 Carsten Ehrhardt (TCD) - Cell culture models of the air-blood barrier
10.00 - 10.30 Markus Fridén (Uppsala Universitet) - Precision-cut lung slices for profiling of inhaled compounds
10.30 - 11.00 Coffee break
11.00 - 11.30 Ben Forbes (Kings College London) - Isolated and perfused lung models
11.30 - 12.00 Chris Edwards (GSK) - A novel Quantitative Structure-Activity Relationship (QSAR) model to Accurately Predict Pulmonary Absorption
12.00 - 12.30 Per Bäckman (Mylan) - Modelling airway epithelial permeability - when do we need to care and what do we need to know?
12.30 - 13.00 Wrap-up of session 1
13.00 - 14.00 Lunch break
Session 2 Drug transporter effects on pulmonary PK - case studies
Chair - Yukio Kato
Rapporteurs - Markus Fridén and Ben Forbes
14.00 - 14.30 Mark Gumbleton (Cardiff University) - P-gp in the lungs
14.30 - 15.00 Carsten Ehrhardt (TCD) - Interaction of organic cation transporters with bronchodilators in vitro, ex vivo and in vivo
15.00 - 15.30 Mikihisa Takano (Hiroshima University) - Functional expression of PEPT2 and its regulation in alveolar epithelial cells
15:30 - 16:00 Ken-ichi Hosoya (University of Toyama) - Implications of the carrier-mediated transport of nicotine in lung and other tissues
16.00 - 16.30

Wrap-up of session 2

16.30 - 19.00 Dublin City Tour (incl. visit of the Teeling distillery)
19.00 - 22.30 Dinner and Hooley Show at Johnnie Fox's Pub
   

Friday, 23rd September

Time Activity
Session 3 Transporters as drug targets
Chair - Mikihisa Takano
Rapporteurs - Per Bäckman and Chris Edwards
09.00 - 09.30 Yukio Kato (Kanazawa University) - Organic cation transporter OCTN1 as possible target for lung pathology
09.30 - 10.00 Takeo Nakanishi (Kanazawa University) - Pathophysiological role of prostaglandin transporter OATP2A1/SLCO2A1 in pulmonary fibrosis
10.00 - 10.30 William Couet (Université de Poitiers) - Pulmonary transporters in the drug disposition of antibiotics
10.30 - 11.00 Wrap-up of session 3
11.00 - 11.30 Coffee break
11.30 - 12.00

Chris Keely (TR&I) - Funding opportunities for multinational consortia

12.00 - 13.00 Plenum discussion
13.00 - 14.00 Lunch break
14.00 - 17.00 Lab session on uptake and transport studies in cell cultures
19.00 - 22.30 Dinner
   

carstenworkshop6

carstenworkshop2 carstenworkshop4

carstenworkshop5 carstenworkshop7

carstenworkshop8


Last updated 31 January 2017 by School of Pharmacy & Pharmaceutical Sciences (Email).